Anemia following surgery for morbid obesity

Apr 19, 2010

A research team from United States evaluated the long-term heath issues of patients who underwent gastric bypass surgery. They found menstruating females and patients with peptic ulcer disease are at greatest risk of developing anemia following gastric bypass surgery.

Morbid obesity is one of the most common causes of morbidity and mortality in Western countries. Roux-en-Y gastric bypass (RYGB) has become a common procedure for achieving short- and long-term weight loss. It has gained great popularity among surgeons and patients in recent years. Long-term complications are still being discovered. Because of the altered anatomy, absorption of iron from the proximal is impaired. Anemia develops in some patients with inadequate oral supplementation or chronic occult .

A research article to be published on April 21, 2010 in the addresses this question. A research team led by Dr. I Michael Leitman evaluated the incidence and risk factors for the development of anemia after Roux-en-Y gastric bypass (RYGB).

They found twenty-one of 206 (10.2%) patients developed anemia at some point during the post-operative period. Following statistical analysis, patients with the greatest risk for anemia were menstruating females and patients found to have marginal ulcer on endoscopy. In all cases anemia was due to (low , elevated total iron binding capacity, and low mean corpuscular volume).

This study concluded that increased ferrous sulfate supplementation may be necessary to prevent iron depletion in populations at increased risk of developing iron deficiency anemia after RYGB surgery, such as menstruating women and patients with peptic ulcer disease.

Explore further: Ulcer-causing bacteria induces stomach stem cell growth in mice, researchers find

More information: Avgerinos DV, Llaguna OH, Seigerman M, Lefkowitz AJ, Leitman IM. Incidence and risk factors for the development of anemia following gastric bypass surgery. World J Gastroenterol 2010; 16(15): 1867-1870. www.wjgnet.com/1007-9327/full/v16/i15/1867.htm

Related Stories

Gastric bypass surgery increases risk of kidney stones

Mar 10, 2010

March 11, 2010 - Patients who undergo gastric bypass surgery experience changes in their urine composition that increase their risk of developing kidney stones, research from UT Southwestern Medical Center investigators suggests.

Genetic form of anemia defined molecularly

Apr 01, 2010

Sideroblastic anemia is a form of anemia caused by an inability to incorporate iron into hemoglobin, something that is essential if the molecule is to perform its vital function of carrying oxygen from the lungs to the tissues. ...

Recommended for you

How proteins evolved the capacity for movement within cells

17 hours ago

The process behind how the molecular components of living organisms start to move has been explained for the first time in new research published by Science and it is an intricate set of dance steps where the tempo is set ...

How do neural cells respond to ischemia?

18 hours ago

A group of researchers from the Lomonosov Moscow State University, in collaboration with their Irish colleagues from the University College Cork, has studied the early response of cells to ischemia, which ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.