Combining weight-focused counseling, medication helps women quit smoking

March 22, 2010

For women smokers worried about their weight, combining cognitive behavioral therapy addressing weight concerns with the medication bupropion appears more effective than counseling alone to help them quit smoking, according to a report in the March 22 issue of Archives of Internal Medicine.

"Many women smokers are concerned about the that commonly accompanies an attempt to ," the authors write as background information in the article. These women are less likely to attempt quitting, are more likely to drop out of treatment and gain more weight after quitting than those who don't report weight-related concerns. Previous efforts to add weight control interventions to smoking cessation interventions have proved ineffective, the authors note.

Michele D. Levine, Ph.D., of the University of Pittsburgh Medical Center, and colleagues conducted a randomized, double-blind, placebo-controlled trial with 349 women smokers who were concerned about their weight. Of these, 106 were assigned to take the medication bupropion and also participate in CONCERNS, a program focusing on weight gain issues. An additional 87 participated in CONCERNS while taking placebo, 89 received counseling without a weight gain focus while taking bupropion and 67 underwent standard counseling while taking placebo. Participants took medications for six months and participated in counseling for three months.

Overall, 31.8 percent of women abstained from smoking for three months, 21.8 percent after six months and 16.3 percent after 12 months. Bupropion improved abstinence rates among women receiving the CONCERNS intervention; those taking active medication were more likely than those taking placebo to have quit at three months (40.6 percent vs. 18.4 percent), six months (34 percent vs. 11.5 percent) and 12 months (23.6 percent vs. 8.1 percent). They were also slower to relapse, with a median or midpoint of 266 days vs. 46 days to relapse.

However, bupropion did not appear to improve quit rates or time to relapse among those receiving standard counseling, the authors note. In addition, there were no differences among women who quit in either average weight gain or their level of concern about weight gain.

"Future research should focus on possible mechanisms to explain the efficacy of this specialized counseling plus bupropion therapy and address issues related to the practicality of wider dissemination of the specialized counseling intervention for weight-concerned women smokers," the authors conclude. "These results may also serve to guide further development of pharmacologic and behavioral approaches for smokers with other comorbid concerns."

Explore further: New moms who quit smoking fear weight gain

More information: Arch Intern Med. 2010;170[6]:543-550.

Related Stories

New moms who quit smoking fear weight gain

September 18, 2006

Researchers in Pittsburgh say nicotine addiction does not explain why so many women who quit smoking during pregnancy resume the habit after delivery.

Drug may help women stop smoking

October 9, 2006

Adding the opiate blocker naltrexone to the combination of behavioral therapy and nicotine patches boosted smoking cessation rates for women by almost 50 percent when assessed after eight weeks of treatment, but made no difference ...

Recommended for you

How the finch changes its tune

August 3, 2015

Like top musicians, songbirds train from a young age to weed out errors and trim variability from their songs, ultimately becoming consistent and reliable performers. But as with human musicians, even the best are not machines. ...

Machine Translates Thoughts into Speech in Real Time

December 21, 2009

( -- By implanting an electrode into the brain of a person with locked-in syndrome, scientists have demonstrated how to wirelessly transmit neural signals to a speech synthesizer. The "thought-to-speech" process ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.