Heart test found safe for pre-transplant kidney patients

Oct 15, 2009

A screening test that measures whether a patient's heart is healthy enough for a kidney transplant is not as dangerous as once thought, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The findings indicate that the test, called coronary angiography, does not cause a decline in kidney function for patients with advanced chronic kidney disease (CKD) and can help determine when to schedule a patient for transplantation.

CKD may contribute to the development of heart disease, so physicians keep a close eye on CKD patients' heart health. However, they are reluctant to perform —which uses dye and x-rays to show the inside of the heart's arteries—in CKD patients, who are thought to have an increased risk of experiencing complications from the procedure. This is unfortunate because coronary angiography can help determine whether a patient is healthy enough to undergo a kidney transplant.

To determine the true risks of the test for patients with advanced CKD, Nicky Kumar, MBChB, MRCP (West London Renal and Transplant Centre, Imperial College Kidney and Transplant Institute, London), and her colleagues analyzed 76 patients with late stage CKD who were potential transplant recipients seen at their clinics from 2004 to 2007. Kidney function measurements were recorded 12 months before and 12 months after patients underwent coronary angiography.

The researchers found that patients' kidney function was similar before and after coronary angiography, indicating that the procedure was not harmful to the kidneys. The detected in 23 patients, making them unsuitable for transplantation until their heart complications were addressed. Twenty-two patients' tests indicated that they were healthy enough to receive a transplant instead of going on dialysis. This kind of information is key to optimal patient care, since administering a before the patient needs dialysis is the most effective treatment for CKD.

More information: "Effect of Elective Coronary Angiography on Glomerular Filtration Rate in Patients with Advanced Chronic Kidney Disease," doi 10.2215/CJN.01480209

Source: American Society of Nephrology (news : web)

Explore further: Doctors' checklist could help decrease length of COPD patients' hospital stay

Related Stories

Low thyroid function common in chronic kidney disease

Jun 11, 2008

Many patients with chronic kidney disease (CKD) have mild reductions in thyroid function, or subclinical hypothyroidism—a condition that becomes more common as kidney function declines, according to a study in the September ...

Recommended for you

Score IDs patients with upper extremity DVT at low risk

5 hours ago

(HealthDay)—For patients with upper-extremity deep vein thrombosis (DVT), six easily available factors can be used to create a score that identifies those at low risk of adverse events during the first ...

Combined drug treatment combats kidney disease

15 hours ago

A recent discovery by drug researchers whereby coupling specific cell membrane receptors has altered kidney cell function has triggered a re-think of how to treat chronic kidney disease (CKD) more effectively.

Active substance targeting dreaded hospital germs

15 hours ago

In the German Center for Infection Research (DZIF), scientists have conducted clinical studies on an active substance against the dreaded hospital pathogen Staphylococcus aureus: a highly effective protein from bacteriophages ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.