'It takes a genome: How a clash between our genes and modern life is making us sick'

Feb 25, 2009

It's not just the climate that is struggling with what humans have done to the modern world, our genes are feeling the pressure as well, according to Professor Greg Gibson's recently published book.

In It Takes a Genome: How a Clash Between Our Genes and Modern Life Is Making Us Sick, Professor Gibson, from UQ's School of Biological Sciences, suggests the increased rates of diseases such as diabetes, cancer and Alzheimer's are due to human genes being unable to cope with the 21st century Western lifestyle.

"In the last two generations or so, we've changed our environment so much in terms of what we eat, what pathogens we are exposed to and the stresses we put on ourselves psychologically," Professor Gibson said.

"The rapid cultural change means our genes are no longer in a comfort zone - that's pushed us outside of the realm that the genome can normally tolerate.

"Because of that, we've gone from one percent of people being susceptible to these diseases to more like 10 or 15 percent."

Detailed in the book is the idea that, because genes evolve at a much slower rate than the environment changes, disease epidemics cannot be attributed solely to genetic susceptibility. Rather, environmental change is to blame.

Professor Gibson said while being able to identify the genes responsible for certain diseases was an exciting advancement in genetics, it didn't necessarily mean we were closer to predicting who would get sick.

"If we know our genes we have a better guess at who's predisposed to certain diseases, but we have to understand a whole lot more than that," he said.

"This book actually started out as a response to Richard Dawkin's The Selfish Gene, so I wanted to get the message across that, rather than us being robots that are slaves to our genes, genes are communities that work together."

The ideas in It Takes a Genome are the culmination of 10 years' research analysing how the genomes of various animals respond to environmental change.

The book is available to purchase online and is aimed at a non-scientific audience.

Professor Gibson is an Australian Professorial Fellow in UQ's School of Biological Sciences, having moved recently from North Carolina State University.

Source: Research Australia

Explore further: Hospice use linked to fewer depressive symptoms for surviving spouses

Related Stories

Architects to hatch Ecocapsule as low-energy house

18 hours ago

Where people call home depends on varied factors, from poverty level to personal philosophy to vanity to community pressure. Ecocapsule appears to be the result of special factors, a team of architects applying ...

California farmers agree to drastically cut water use

22 hours ago

California farmers who hold some of the state's strongest water rights avoided the threat of deep mandatory cuts when the state accepted their proposal to voluntarily reduce consumption by 25 percent amid ...

Apple may deliver ways to rev up the iPad, report says

22 hours ago

MacRumors last month said that the latest numbers from market research firm IDC's Worldwide Quarterly Tablet Tracker revealed Apple stayed on as the largest vendor in a declining tablet market. The iPad ...

Recommended for you

Tackling child abuse in Africa with research and fun

2 hours ago

In one of South Africa's poorest areas, an imaginative new parenting programme is tackling the physical and emotional abuse of children. Oxford University's Vice-Chancellor, Professor Andrew Hamilton, travelled ...

User comments : 1

Adjust slider to filter visible comments by rank

Display comments: newest first

menkaur
not rated yet Feb 26, 2009
yeah.. back to nature... let's live without antibiotics, medicine, computers, internet and everything else...
if i'm not mistaken, the people at that era had life expectancy of - how many? - 30 years?

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.