WHO tool helps target bone treatment

December 3, 2008

Better targeted, more cost-effective osteoporosis treatment could soon be a reality worldwide. A new method for determining more accurately at which point someone needs further diagnostic tests, or when immediate treatment is warranted, has been developed by The National Osteoporosis Guideline Group in the UK.

Rather than relying primarily on Bone Mineral Density (BMD) measurements, as the majority of current guidelines do, their approach takes into account both the risk of someone suffering a fracture – using the WHO's fracture risk assessment tool, FRAX® - as well as whether or not treatment is likely to be cost-effective. This new method, developed by Professor John A. Kanis and colleagues from the WHO Collaborating Centre for Metabolic Bone Diseases at the University of Sheffield Medical School in the UK, already forms the basis of the new clinical guidelines for the management of osteoporosis in the UK. The case finding on the management of osteoporosis with FRAX® has been published in Springer's journal Osteoporosis International.

Professor Kanis, President of the International Osteoporosis Foundation, comments: "The incorporation of the WHO risk assessment tool FRAX into practice guidelines in the UK is a key development that will target treatment more accurately to those in need and avoid unnecessary treatment in men and women at low risk. I hope that this paper in Osteoporosis International will serve as a template for the development of FRAX-based guidance in other countries."

The FRAX® tool predicts the ten-year risk of men and women suffering a fracture. An individual's age, sex, weight, height, and femoral BMD, if available, are entered into the web-based tool, followed by clinical risk factors for osteoporosis including a prior fracture, parental history of hip fracture, smoking, long-term use of glucocorticoids (a type of steroid hormone), rheumatoid arthritis and alcohol consumption. The tool then calculates the likelihood of the individual suffering a fracture in the next ten years.

Because this new method for the management of osteoporosis takes into account the likelihood of someone suffering a fracture, rather than relying solely on BMD, or BMD with one or more recognized clinical risk factors, it is an important milestone towards helping health professionals worldwide to identify patients at high risk of fracture more accurately and treat them cost-effectively.

Source: Springer

Explore further: Move it or lose it: One-year mission video miniseries

Related Stories

Move it or lose it: One-year mission video miniseries

March 12, 2015

Have you ever noticed after lying in bed sick for a few days that standing upright took you a moment to regain your balance? Or perhaps you have an aging grandparent who spends more time lying in bed than standing and you ...

Stepping stones to NASA's human missions beyond

January 21, 2015

"That's one small step for (a) man; one giant leap for mankind." When Neil Armstrong took his first steps on the moon, many strides came before to achieve that moment in history. The same is true for a human mission to Mars. ...

Computerized osteoporosis detection

October 1, 2012

A computerized approach to examining patient bone X-rays for diagnosis of osteoporosis could side-step the subjectivity associated with visual examination, according to a new research paper in the International Journal of ...

Recommended for you

Machine Translates Thoughts into Speech in Real Time

December 21, 2009

(PhysOrg.com) -- By implanting an electrode into the brain of a person with locked-in syndrome, scientists have demonstrated how to wirelessly transmit neural signals to a speech synthesizer. The "thought-to-speech" process ...

Quantum Theory May Explain Wishful Thinking

April 14, 2009

(PhysOrg.com) -- Humans don’t always make the most rational decisions. As studies have shown, even when logic and reasoning point in one direction, sometimes we chose the opposite route, motivated by personal bias or simply ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.