Lab will pay to infect people with malaria

March 6, 2008

Scientists in Seattle plan to pay people to catch malaria in order to test the safety and efficacy of new vaccines.

The Seattle Biomedical Research Institute and the PATH Malaria Vaccine Initiative are collaborating to build a Human Challenge Center at SBRI to test new interventions against the deadly malaria parasite. "This center will allow us to greatly increase our ability to evaluate whether a new vaccine formulation should advance to testing in clinical trials in malaria-endemic populations," Dr. Christian Loucq of MVI said Wednesday in a statement.

The laboratory's Malaria Clinical Trials Center will be one of only a handful of facilities of its kind in the world. Volunteers inoculated with a malaria vaccine candidate will be deliberately infected with malaria through the bite of malaria-infected mosquitoes to assess whether or not the candidate vaccine can prevent or delay malaria infection.

The Seattle Times said the strain of malaria used in the testing is a cloned strain that can be quickly cured. More than 900 people have participated in similar tests at Walter Reed Army Institute of Research. There are also labs in Britain and the Netherlands, the newspaper said.

Copyright 2008 by United Press International

Explore further: Mosquitoes deliver malaria 'vaccine' through bites

Related Stories

Mosquitoes deliver malaria 'vaccine' through bites

July 29, 2009

In a daring experiment in Europe, scientists used mosquitoes as flying needles to deliver a "vaccine" of live malaria parasites through their bites. The results were astounding: Everyone in the vaccine group acquired immunity ...

Gates: $258 million for malaria research

October 31, 2005

The Bill and Melinda Gates Foundation has given $258 million in malaria research grants. The foundation says malaria kills an estimated 2,000 African children each day and takes the lives of more than 1 million people worldwide ...

Bill Gates says innovation can leverage change

January 25, 2010

(AP) -- The needs of the poor are greater than the money available to help them, but that's not enough to discourage Bill Gates in his work as co-chair of the world's largest charitable foundation.

Forgotten evolutionist lives in Darwin's shadow

June 28, 2009

(AP) -- As he trudges past chest-high ferns and butterflies the size of saucers, George Beccaloni scours a jungle hilltop overlooking the South China Sea for signs of a long-forgotten Victorian-era scientist.

Recommended for you

How the finch changes its tune

August 3, 2015

Like top musicians, songbirds train from a young age to weed out errors and trim variability from their songs, ultimately becoming consistent and reliable performers. But as with human musicians, even the best are not machines. ...

Machine Translates Thoughts into Speech in Real Time

December 21, 2009

( -- By implanting an electrode into the brain of a person with locked-in syndrome, scientists have demonstrated how to wirelessly transmit neural signals to a speech synthesizer. The "thought-to-speech" process ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.