Human Proteinpedia: Portal to share human protein data among scientific community

March 14, 2008

Today, scientists have access to a large amount of biological information through the Internet. Nevertheless, these databases do not always have the endorsement of experimental evidence, and are usually distributed in several web locations, a fact that makes information retrieval difficult to achieve.

The Human Proteinpedia (www.humanproteinpedia.org) is born from this need to break down barriers. It is a protein “Wikipedia”, pioneer in this area, allowing researchers to share and integrate -freely- information regarding the set of proteins expressed by the human genome.

This new resource of scientific information would not have been possible without the participation of 71 laboratories of genetics and proteomics from around the globe. The Spanish participation in this project is represented by the Research Group on Human Genetics, of the Institut d’Investigacions August Pi i Sunyer (IDIBAPS)/Faculty of Medicine (Universitat de Barcelona), with Dr. Rafael Oliva, Dr. Juan Martínez-Heredia, and Dr. José Manuel Vidal, and the Unit of Genomics and Proteomics of the Cancer Research Centre (Universidad de Salamanca-CSIC) led by Dr. Xosé R. Bustelo and Dr. Nieves Ibarrola.

The main objective of the Human Proteinpedia is to promote the exchange of genetic information among researchers. With this aim, it offers a standard and centred vision of the proteome, i. e., the whole of sequences of proteins encoded by the human genome and information associated to it. Registered users will be able to include, retrieve and share data about sequences, structures or mutations validated by experimental evidence, since original information can only be modified by the user that has contributed that piece of data.

Thus, the information deposited in the Human Proteinpedia forms an unprecedented database which helps comparing and interpreting protein sequences supplied by the scientific community. The main aim of this tool, which has been under operation for about a year, is to integrate and share the identification and sequencing of proteins in published studies, which will permit to make progress in the study of genes and of the proteins involved in human pathologies.

Source: IDIBAPS

Explore further: 'Bacterial litmus test' provides inexpensive measurement of micronutrients

Related Stories

Biological tools create nerve-like polymer network

August 24, 2015

Using a succession of biological mechanisms, Sandia National Laboratories researchers have created linkages of polymer nanotubes that resemble the structure of a nerve, with many out-thrust filaments poised to gather or send ...

How zebrafish rebuild the skeleton of amputated fins

August 24, 2015

Fish, in contrast to humans, have the fascinating ability to fully regenerate amputated organs. The zebrafish (Danio rerio) is a popular ornamental fish. When parts of its tailfin are injured by predators, or are experimentally ...

Key protein in cilia assembly identified

August 21, 2015

The group led by ICREA Research Professor Cayetano Gonzalez at IRB Barcelona, in collaboration with the group of Professor Giuliano Callaini from the University of Siena in Italy, has published a new study in Current Biology ...

Team identifies structure of tumor-suppressing protein

August 20, 2015

An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN. Their findings provide ...

Recommended for you

How the finch changes its tune

August 3, 2015

Like top musicians, songbirds train from a young age to weed out errors and trim variability from their songs, ultimately becoming consistent and reliable performers. But as with human musicians, even the best are not machines. ...

Machine Translates Thoughts into Speech in Real Time

December 21, 2009

(PhysOrg.com) -- By implanting an electrode into the brain of a person with locked-in syndrome, scientists have demonstrated how to wirelessly transmit neural signals to a speech synthesizer. The "thought-to-speech" process ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.