Dangerous diarrheal bacterium found on asymptomatic patients

Sep 21, 2007

The bacterium that causes a highly contagious and sometimes deadly form of diarrhea is frequently carried by persons who do not have any of the disease symptoms, according to a study in the Oct. 15 issue of Clinical Infectious Diseases, now available online. These findings have dramatic implications for health care workers who have customarily treated and isolated only those patients who exhibit symptoms.

Clostridium difficile-associated disease (CDAD) is the most common health care-associated diarrheal disease in developed countries, with most infections occurring in hospitals, nursing homes, or other institutions. Generally, control measures have focused on placing patients with suspected or documented CDAD under contact precautions until the diarrhea resolved, then disinfecting their rooms. These infection control measures have been effective in reducing, but not eliminating, CDAD outbreaks.

This study offers reasons why those infection control efforts haven’t been more successful: the bacteria may be thriving on asymptomatic patients and items in their immediate vicinity such as call buttons, bed rails, bedside tables, and telephones. The researchers found that spores were easily transferred from the patient’s skin to investigators’ hands.

“Our findings suggest that asymptomatic carriers of epidemic and non-epidemic C. difficile strains could contribute significantly to transmission in long-term care facilities,” said senior author Curtis Donskey, MD, of the Louis Stokes Cleveland VA Medical Center. “Simple modifications of current infection control practices, including glove use by health care workers and use of 10 percent bleach for room disinfection, could reduce the risk of transmission from asymptomatic carriers.”

Current guidelines recommend discontinuation of contact precautions for CDAD patients after diarrhea resolves. However, the authors found that nearly 25 percent of the asymptomatic carriers were patients who had previously had CDAD. Therefore, they propose extending the duration of contact precautions until the patient is discharged.

Source: Infectious Diseases Society of America

Explore further: Washington woman's measles death is first in US since 2003

Related Stories

Light echo helps researchers map out parts of galaxy

26 minutes ago

Thousands of years before humans invented agriculture, a bright burst of X-rays left the dense neutron star Circinus X-1, located in the faint Southern constellation Circinus. A year and a half ago, those ...

Cuban, US scientists bond over big sharks

56 minutes ago

Somewhere in the North Atlantic right now, a longfin mako shark—a cousin of the storied great white—is cruising around, oblivious to the yellow satellite tag on its dorsal fin.

Gimmicks and technology: California learns to save water

1 hour ago

Billboards and TV commercials, living room visits, guess-your-water-use booths, and awards for water stinginess—a wealthy swath of Orange County that once had one of the worst records for water conservation ...

Recommended for you

Federal government to step up bird flu monitoring this fall

12 hours ago

The federal government announced plans Thursday to step up monitoring wild birds for avian influenza this fall to provide an early warning of any resurgence of a disease that devastated poultry farms in the Upper Midwest.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.