Testosterone patch benefits women with low sexual desire

Aug 14, 2007

Novel research published in the current issue of The Journal of Sexual Medicine supports the claim that women with hypoactive sexual desire disorder or HSDD (persistent or recurrent deficiency and/or absence of sexual fanatasies/thoughts, and/or desire for, or receptivity to, sexual activity, which causes personal distress) show noted improvement in sexual desire and sexual function following low dose testosterone treatment.

Two randomized double-blind, placebo controlled trials in surgically postmenopausal (uterus and ovaries removed) women with HSDD demonstrated that transdermal testosterone patch treatment resulted in significant improvements in the frequency of satisfying sexual activity and sexual desire, as well as a decrease in sexual distress.

A total of 132 participants from the 2 trials were interviewed after a 6-month treatment period regarding their experience with the treatment. Results revealed a significant increase in frequency of satisfying sexual activity and sexual desire based on women experiencing the treatment as beneficial. Those women had an average increase in sexual activity of 4.4 times per 4 weeks. In contrast, women who did not experience a benefit had only a 0.5 increase in activity per 4 weeks.

“More women on testosterone experienced a meaningful benefit (52 percent vs. 31 percent) and, in fact, the odds of experiencing a meaningful benefit on testosterone were 2.4 times greater than that of placebo,” says Sheryl Kingsberg, principal author of the study. Since the women were also able to judge for themselves whether or not the treatment was beneficial, those who experienced benefit were interested in continuing treatment.

“These findings not only confirm the clinical effectiveness of transdermal testosterone, but provide benchmarks for the degree of improvement in sexual function that all future therapies for this disorder should try to attain,” says Jan Shifren, co-author of the study.

"This is an especially relevant clinical study in the field of sexual medicine," said Dr. Irwin Goldstein, Editor-in-Chief of The Journal of Sexual Medicine. "These important data reinforce the positive value that treatment with the low dose testosterone patch can bring to the quality-of-life of surgically post-menopausal women with HSDD."

Source: Blackwell Publishing

Explore further: AMA: avoiding distress in medical school

Related Stories

The truth behind handshake-sniffing may bum you out

Mar 09, 2015

As we all know, a firm handshake is important in making a good first impression. It's a sure sign of physical strength and, rightly or wrongly, we use it make all manner of judgements about character, personality ...

Large testicles are linked to infidelity

Jan 29, 2014

There is a clear correlation between the size of the testicles of male primates and the proneness to infidelity of females. Learn more about sex, sperm and infidelity at the anniversary exhibition Sexus.

Recommended for you

AMA: avoiding distress in medical school

May 22, 2015

(HealthDay)—Understanding the key drivers underlying medical students' distress can help address the issues and enhance student well-being, according to an article published by the American Medical Association.

European court to rule on right-to-die case

May 21, 2015

Europe's human rights court will on June 5 rule on whether a man in a vegetative state can be taken off life support, a case that has ignited a fierce euthanasia debate in France, a spokesman said Thursday.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.