Scientists work to 'camouflage' devices

May 17, 2007

Two U.S. researchers have received a government grant to study ways to prevent the body from developing scar tissue around implanted biomedical devices.

Florida State University Professor Joseph Schlenoff and Associate Professor Thomas Keller have been awarded a four-year, $1 million grant from the National Institutes of Health. Together, they will work to develop ways of coating coronary stents, synthetic heart valves and other biomedical devices with thin films that discourage vascular smooth muscle cells from adhering to their surfaces. Such adhesions often lead to scarring and new blockages.

"For years, surgeons have used stents to reopen clogged coronary arteries -- only to see the stents themselves cause new blockages ...," said Schlenoff. "In our research project, we're looking for ways to 'camouflage' biomedical devices so the body doesn't even know they're there."

The project also involves Michael Davidson, director of the Optical Microscopy group at Florida State University's National High Magnetic Field Laboratory; Scott Olenych, a postdoctoral researcher; and Maroun Moussallem, a graduate student in the Schlenoff lab.

Davidson will provide molecular photographs that chronicle the interaction, or lack thereof, between the researchers' polymers and biological cells.

Copyright 2007 by United Press International

Explore further: New strategies against rare, fatal lung syndrome

Related Stories

California oil spill gushed like hose 'without a nozzle'

50 minutes ago

Firefighters investigating a reported petroleum stench at a California beach last month didn't take long to find a spill—oil was spreading across the sand and into the surf. Tracing the source, they found ...

Recommended for you

New strategies against rare, fatal lung syndrome

7 hours ago

Hermansky-Pudlak syndrome (HPS) patients suffer symptoms including albinism, visual impairment, and slow blood clotting, but what makes some versions of the genetic condition fatal is that patients with some ...

How a newborn baby sees you

15 hours ago

A newborn infant can see its parents' expressions at a distance of 30 cm. For the first time researchers have managed to reconstruct infants visual perception of the world.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.