New proteins detected on silicone breast implants

Dec 19, 2006

Scientists in Austria are reporting detection of previously unrecognized proteins that accumulate on the surface of silicone breast implants after implants are in the body. Georg Wick and colleagues say that the proteins may be involved in causing immune reactions in patients from breast implants and other types of silicone implants.

Their research involved 23 healthy women who were undergoing breast augmentation for cosmetic reasons, including some who were removing or replacing implants due to complications.

In an article in the current (December) issue of ACS' Journal of Proteome Research, a monthly publication, the scientists describe using a targeted proteomics approach to identify proteins adsorbed to the surface of silicone because those proteins have been identified as key components in local immune reactions to silicone. "Thus far we have identified the 30 most abundant proteins deposited on the surface of silicone, the largest known inventory of such proteins so far."

Noting uncertainty about any link between autoimmune disease and silicone implants, they state that the new report "shows that silicone promotes at least the adhesion of altered self-proteins, which in turn may trigger an autoimmune response of the immune system."

Source: ACS

Explore further: Life-prolonging protein could inhibit ageing diseases

Related Stories

Recommended for you

Life-prolonging protein could inhibit ageing diseases

May 29, 2015

Researchers have found a molecule that plays a key link between dietary restriction and longevity in mammals. This discovery may lead to the development of new therapies to inhibit age-related diseases.

How sleep helps us learn and memorize

May 28, 2015

Sleep is important for long lasting memories, particularly during this exam season. Research publishing in PLOS Computational Biology suggests that sleeping triggers the synapses in our brain to both streng ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.