Study: Live H5N1 virus vaccines effective

September 12, 2006

U.S. scientists say live, weakened versions of differing strains of avian flu viruses have offered protection when tested in mice and ferrets.

Researchers say their findings are encouraging because they demonstrate the ability to create a vaccine based on one particular strain of the H5N1 flu virus that could potentially protect against different emerging H5N1 flu strains.

"If an influenza pandemic were imminent or under way, we would need a vaccine that could stimulate immunity quickly, preferably with a single dose," said Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases. "The encouraging findings of this study suggest vaccines based on live, but weakened, versions of the H5N1 avian influenza virus may quickly stimulate protective immunity.

"We are further exploring this live, attenuated vaccine strategy as one of several tools that we hope to have available in the event of an influenza pandemic," he added.

Senior investigator Dr. Kanta Subbarao and co-chief investigator Dr. Brian Murphy explain the research in the Sept. 12 issue of PLoS Medicine.

Copyright 2006 by United Press International

Explore further: Emergency preparedness in zoos and aquariums

Related Stories

Emergency preparedness in zoos and aquariums

November 17, 2014

You need only look at the papers or television news to see the reports. Infectious disease outbreaks, weather emergencies and disasters both natural and man-made. They're all not just threats to human populations – they ...

Researchers develop mRNA based flu vaccine

November 26, 2012

(Phys.org)—A joint research effort by the Friedrich-Loeffler-Institute and pharmaceutical company CureVac, both based in Germany, has resulted in the creation of a new type of flu vaccine. The vaccine, as the team describes ...

House finches 'avoid sick members of their own'

November 7, 2012

House finches avoid sick members of their own species, scientists said in a finding that could be useful for tracking the spread of diseases like bird flu that also affects humans.

Recommended for you

Expanding theory of evolution

August 5, 2015

An Indiana University professor is part of an international team of biologists working to expand Darwin's theory of evolution to encompass factors that influence a species' growth and development beyond genetics—as well ...

Can genes make us liberal or conservative?

August 4, 2015

Aristotle may have been more on the money than he realised in saying man is a political animal, according to research published Wednesday linking genes with liberal or conservative leanings.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.