Prostate cancer: Major risk for blacks

August 22, 2006

U.S. researchers have identified a DNA segment on chromosome 8 that is a major risk factor for prostate cancer, especially in African-American men.

"This paper identifies a genetic risk factor that about doubles the likelihood of prostate cancer in younger African-American men," says Harvard Medical School Assistant Professor of Genetics David Reich, the lead investigator of the study. "This finding may explain why younger African-Americans have an increased risk for prostate cancer than do other populations -- and may also explain why this increased risk in African-Americans attenuates with older age."

The lead author of the study, Dr. Matthew Freedman, a Harvard Medical School instructor at the Dana-Farber Medical School, said the finding is one of the first genetic risk factors found responsible for an appreciable fraction of sporadic prostate cancer cases.

"Interestingly," said Freedman, "we found that this region also confers risk for prostate cancer for diverse ethnic groups. The actual gene, however, remains to be identified."

The study is detailed in the online early edition of the Proceedings of the National Academy of Sciences.

Copyright 2006 by United Press International

Explore further: After years of forensic investigation, Somerton Man's identity remains a mystery (Part 2: DNA, isotopes, and autopsy)

Related Stories

Chlordecone exposure and risk of prostate cancer

June 22, 2010

In an article to be published on 21 June 2010 in the Journal of Clinical Oncology, researchers from Inserm (Inserm unit 625 - Research Group on Human and Mammalian Reproduction, University of Rennes 1), the CHU (University ...

Infertility increases a man's risk of prostate cancer

March 22, 2010

Infertile men have an increased risk of developing high grade prostate cancer, which is more likely to grow and spread quickly. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal ...

Prostate cancer therapy can increase heart risk factors

February 2, 2010

Androgen-deprivation therapy (ADT), commonly used to treat prostate cancer, can worsen heart risk factors and may increase the risk of heart attack and/or cardiac death, although the relationship between ADT and heart attack ...

Recommended for you

How bees naturally vaccinate their babies

July 31, 2015

When it comes to vaccinating their babies, bees don't have a choice—they naturally immunize their offspring against specific diseases found in their environments. And now for the first time, scientists have discovered how ...

Image: Hubble sees a dying star's final moments

July 31, 2015

A dying star's final moments are captured in this image from the NASA/ESA Hubble Space Telescope. The death throes of this star may only last mere moments on a cosmological timescale, but this star's demise is still quite ...

Exoplanets 20/20: Looking back to the future

July 31, 2015

Geoff Marcy remembers the hair standing up on the back of his neck. Paul Butler remembers being dead tired. The two men had just made history: the first confirmation of a planet orbiting another star.

Earth flyby of 'space peanut' captured in new video

July 31, 2015

NASA scientists have used two giant, Earth-based radio telescopes to bounce radar signals off a passing asteroid and produce images of the peanut-shaped body as it approached close to Earth this past weekend.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.