Unusual flu vaccine is developed

Jun 14, 2006

U.S. scientists have used reverse genetics to develop an influenza virus with two key proteins on its surface derived from the H5N1 avian virus strain.

As nations stockpile vaccines against H5N1, the strain of influenza virus that experts fear could cause the next flu pandemic, researchers are unsure if the vaccines will remain effective as the virus mutates.

Dr. Elena Govorkova, Robert Webster and colleagues at St. Jude Children's Research Hospital in Memphis, say they inactivated the virus and used it to vaccinate ferrets.

They said the vaccine protected ferrets from becoming sick when exposed not only to the flu strain from which the vaccine was made, but also two other strains, including a deadly strain labeled A/Vietnam/1203/04.

Cross-strain protection is what would been needed in a pandemic, since it would protect against newly emerging variants until a strain-specific vaccine could be developed.

The scientists said the reverse genetics method they used would allow rapid vaccine preparation, which would be crucial in a fast-moving pandemic.

The study will appear in the July 15 issue of The Journal of Infectious Diseases and is available online.

Copyright 2006 by United Press International

Explore further: Immigrant children given adult dose of hepatitis A vaccine

Related Stories

A new vaccine to fight poultry diseases

Mar 23, 2015

Vaccination is one method used to help prevent the spread of infectious poultry diseases, but current vaccines could be safer and more effective.

Recommended for you

Immigrant children given adult dose of hepatitis A vaccine

20 hours ago

About 250 immigrant children were given an adult dose of a hepatitis A vaccine at a Texas detention facility where they were being held with their mothers, according to U.S. Immigration and Customs Enforcement officials.

Noise from fireworks threatens young ears

Jul 03, 2015

(HealthDay)—The Fourth of July weekend is a time for celebrations and beautiful fireworks displays. But, parents do need to take steps to protect their children's ears from loud fireworks, a hearing expert ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.