Bird flu vaccine not effective in trial

February 17, 2006
Bird Flu

A highly anticipated bird flu vaccine trial in Australia has proven protective for only a small minority of the 400 volunteers in the clinical trial.

Andrew Cuthbertson, the chief scientific officer of the vaccine manufacturer CSL Ltd., said about half who received the highest dose of the vaccine had an immune response comparable to that for regular human flu shots, reported the Sydney Morning Herald Friday.

Those in the trial who received single or smaller doses of the H5N1 bird flu antigen had a response below the threshold for licensing human flu vaccines. However, those receiving the vaccine had no adverse reactions beyond soreness at the injection site.

Cuthbertson said the comparison with ordinary human flu shots was "conservative" and if the deadly strain of bird flu H5N1 mutated to readily infect humans the required dose needed might be different.

CSL will begin a larger trial including children and the elderly who will receive a larger dose of the vaccine, according to Cuthbertson.

Copyright 2006 by United Press International

Explore further: Lush conditions fuel Colorado increase in rabbit fever

Related Stories

Panel backs sharing studies of lab-made bird flu

March 30, 2012

(AP) -- The U.S. government's biosecurity advisers said Friday they support publishing research studies showing how scientists made new easy-to-spread forms of bird flu because the studies, now revised, don't reveal details ...

Controversial 'bird flu' edits move ahead

December 22, 2011

Top US scientists on Wednesday defended their bid to stop details of a mutant bird flu virus from being published and called for global cooperation to ward off an uncontrollable pandemic.

WHO announces deal on sharing flu virus samples

April 17, 2011

The World Health Organisation said Saturday an agreement has been reached on sharing flu virus samples, hammered out after intense negotiations by a group on preparations for flu pandemics.

Universal flu vaccine study yields success in mice

February 18, 2011

( -- Adelaide researchers have taken a step closer to the development of a universal flu vaccine, with results of a recent study showing that a vaccine delivered by a simple nasal spray could provide protection ...

Recommended for you

Horn of Africa drying ever faster as climate warms

October 9, 2015

The Horn of Africa has become increasingly arid in sync with the global and regional warming of the last century and at a rate unprecedented in the last 2,000 years, according to new research led by a University of Arizona ...

Scientists paint quantum electronics with beams of light

October 9, 2015

A team of scientists from the University of Chicago and the Pennsylvania State University have accidentally discovered a new way of using light to draw and erase quantum-mechanical circuits in a unique class of materials ...

A mission to a metal world—The Psyche mission

October 9, 2015

In their drive to set exploration goals for the future, NASA's Discovery Program put out the call for proposals for their thirteenth Discovery mission in February 2014. After reviewing the 27 initial proposals, a panel of ...

What are white holes?

October 9, 2015

Black holes are created when stars die catastrophically in a supernova. So what in the universe is a white hole?


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.