Nanoscale systems for early diagnosis

Jul 14, 2005

A partnership of scientists from the College of Engineering at UC Santa Barbara, Washington University in St. Louis and UC Berkeley have been awarded $12.5 million to develop nanoscale agents to provide early diagnosis and treatment of acute pulmonary and systemic vascular injury over the next five years. The organizations were selected as a collaborative "Program of Excellence in Nanotechnology" (PEN) by the National Heart Lung and Blood Institute of the National Institutes of Health (NIH).

The team, led at UCSB by Professor Craig Hawker, Director of the Materials Research Laboratory, and coordinated by Professor Karen Wooley at Washington University in St. Louis will use nanoscale materials as carriers for diagnostic systems and to deliver therapeutic agents. Hawker and Wooley working with Professor Jean Frechet, PhD, at the University of California, Berkeley, will be developing a way to trigger a breakdown of the nanoparticles after a payload, such as a drug or antiviral agent, is delivered directly to a diseased zone. Targeted nanoparticles will search out arteries that are under stress or are diseased.

The nanoscale designs are based on the concept that advanced nanotechnologies can help overcome inherent limitations of molecular imaging and therapeutic gene transfer.

"I think part of the reason we received this grant was due to UCSB's excellence in soft materials and in engineering," said Hawker. Acute vascular injury and inflammation have been chosen as general targets since they affect tissues broadly, including those of the lung and cardiovascular system.

Source: University of California - Santa Barbara

Explore further: Could computers reach light speed?

Related Stories

Use your smartphone for biosensing

5 hours ago

An Australian research team has shown that smartphones can be reconfigured as cost-effective, portable bioanalytical devices, with details reported in the latest edition of the Open Access Journal 'Sensors'.

Recommended for you

Self-replicating nanostructures made from DNA

9 hours ago

(Phys.org)—Is it possible to engineer self-replicating nanomaterials? It could be if we borrow nature's building blocks. DNA is a self-replicating molecule where its component parts, nucleotides, have specific ...

Could computers reach light speed?

11 hours ago

Light waves trapped on a metal's surface travel nearly as fast as light through the air, and new research at Pacific Northwest National Laboratory shows these waves, called surface plasmons, travel far enough ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.