PLoS Computational Biology is a peer-reviewed computational biology journal established in 2005 and published by the nonprofit Public Library of Science in association with the International Society for Computational Biology. Its Editor in Chief is Philip Bourne. All articles are open access and licensed under the Creative Commons Attribution License. The journal is well-known beyond its core field for its Ten Simple Rules series of articles that capture the essence of selected aspects of research in computational biology or in science more generally, e.g. how to present a poster, how to collaborate, or how to edit Wikipedia. Due to their free licensing, files from PLoS Computational Biology can be reused in places other than the journal s website, e.g. to illustrate Wikipedia articles.
Computer simulations visualize ion flux
Ion channels are involved in many physiological and pathophysiological processes throughout the human body. A young team of researchers led by pharmacologist Anna Stary-Weinzinger from the Department of Pharmacology and Toxicology, ...
Researchers conclude that what causes menopause is—wait for it—men
After decades of laboring under other theories that never seemed to add up, a team led by biologist Rama Singh has concluded that what causes menopause in women is men.
Human Microbiome Project: First detailed studies describe diversity, variety, and function of microbes in people
Human beings are ecosystems on two legs, each of us carrying enough microbes to outnumber our human cells by 10 to 1 and our genes by even more. Identifying the dizzying numbers of bacteria and other microbes that live in ...
Study analyzes dynamical properties in antibiotic resistance enzyme
Antibiotic-resistant bacteria have been emerging at an alarming rate. In some of the scariest of these pathogens, the mechanism responsible for the bacteria's ability to defeat antibiotics is a complex protein molecule embedded ...
New study proposes solution to long-running debate as to how stable the Earth system is
Researchers at the University of Southampton have proposed an answer to the long-running debate as to how stable the Earth system is.
Robot ants successfully mimic real colony behavior
Scientists have successfully replicated the behaviour of a colony of ants on the move with the use of miniature robots, as reported in the journal PLOS Computational Biology.
Was life inevitable? New paper pieces together metabolism's beginnings
(Phys.org)—Describing how living organisms emerged from Earth's abiotic chemistry has remained a conundrum for scientists, in part because any credible explanation for such a complex process must draw from fields spanning ...
Simulating in tiny steps gave birth to long-sought-after method
Using computer simulations to predict which drug candidates offer the greatest potential has thus far not been very reliable, because both small drug-like molecules and the amino acids of proteins vary so much in their chemistry. ...
Birds display lateralization bias when selecting flight paths
Flocks of birds manage to navigate through difficult environments by individuals having predispositions to favour the left- or right-hand side, according to research published in PLOS Computational Biology this week.
Randomness forms complex social structures
(Phys.org)—The environment of group-living animals influences their social behaviour in a stronger way than was previously thought, says a new study from behavioural researchers at ETH and the University of Zurich. They ...