PLoS Computational Biology is a peer-reviewed computational biology journal established in 2005 and published by the nonprofit Public Library of Science in association with the International Society for Computational Biology. Its Editor in Chief is Philip Bourne. All articles are open access and licensed under the Creative Commons Attribution License. The journal is well-known beyond its core field for its Ten Simple Rules series of articles that capture the essence of selected aspects of research in computational biology or in science more generally, e.g. how to present a poster, how to collaborate, or how to edit Wikipedia. Due to their free licensing, files from PLoS Computational Biology can be reused in places other than the journal s website, e.g. to illustrate Wikipedia articles.
Being calm is contagious?
Woodlice are able to calm their excited neighbors according to findings made by Pierre Broly and Jean-Louis Deneubourg of the Free Brussels University (Belgium).
Planarian regeneration model discovered by artificial intelligence
An artificial intelligence system has for the first time reverse-engineered the regeneration mechanism of planaria—the small worms whose extraordinary power to regrow body parts has made them a research ...
Yeast protein network could provide insights into human obesity
A team of biologists and a mathematician have identified and characterized a network composed of 94 proteins that work together to regulate fat storage in yeast.
Who should pay the price?
Social dilemmas, in which an individual profits from selfishness, unless the whole group chooses the selfish option, have long provided an academic challenge. A new study publishing in PLOS Computational Biology theoretically analyz ...
Scientists identify gene required for differentiation of breast stem cells
A novel analytical method has enabled Whitehead Institute scientists to identify a regulatory gene required for breast stem cells to differentiate. Inhibition of this gene, known as RUNX1, prevents cells ...
Short science abstracts that avoid jargon and hype are cited less, study shows
When writing the abstracts for journal articles, most scientists receive similar advice: keep it short, dry, and simple. But a new analysis by University of Chicago researchers of over one million abstracts ...
Modular brains help organisms learn new skills without forgetting old skills
New research suggests that when brains are organized into modules they are better at learning new information without forgetting old knowledge. The findings—published this week in PLOS Computational Bi ...
Bats obey 'traffic rules' when trawling for food
Foraging bats obey their own set of 'traffic rules', chasing, turning and avoiding collisions at high speed, new research from the University of Bristol, UK has found.
Minimizing 'false positives' key to vaccinating against bovine TB
New diagnostic tests are needed to make vaccination against bovine tuberculosis (bovine TB) viable and the number of false positives from these tests must be below 15 out of every 10,000 cattle tested, according ...
Newest computer neural networks can identify visual objects as well as the primate brain
For decades, neuroscientists have been trying to design computer networks that can mimic visual skills such as recognizing objects, which the human brain does very accurately and quickly.
Time management skills keep animals primed for survival
Many animals may have a previously under-appreciated ability to make up for lost time with more effort, according to new research publishing this week in PLOS Computational Biology.
Ebola virus may replicate in an exotic way: Study indicates target for future drugs for measles, Ebola, RSV
University of Utah researchers ran biochemical analysis and computer simulations of a livestock virus to discover a likely and exotic mechanism to explain the replication of related viruses such as Ebola, ...
Life's underlying architecture shapes creation of proteins
Understanding how nature maps sequences of amino acids into the physical structure of the proteins they form is an old problem in biology, and a solution could open new doors to understanding the earliest ...
Solving the puzzle of cooperation in group environments
Research has shown that when two individuals meet repeatedly they are more likely to cooperate with one another. Flávio Pinheiro and colleagues from the Universities of Minho and Lisbon show that the most successful strategy ...
Geometry, programmed death might have enabled evolution of multicellularity
Geometry and programmed cell death may have helped along the evolution of multicellular life, according to new research led by SFI Omidyar Fellow Eric Libby.