PLoS Computational Biology is a peer-reviewed computational biology journal established in 2005 and published by the nonprofit Public Library of Science in association with the International Society for Computational Biology. Its Editor in Chief is Philip Bourne. All articles are open access and licensed under the Creative Commons Attribution License. The journal is well-known beyond its core field for its Ten Simple Rules series of articles that capture the essence of selected aspects of research in computational biology or in science more generally, e.g. how to present a poster, how to collaborate, or how to edit Wikipedia. Due to their free licensing, files from PLoS Computational Biology can be reused in places other than the journal s website, e.g. to illustrate Wikipedia articles.
Newest computer neural networks can identify visual objects as well as the primate brain
For decades, neuroscientists have been trying to design computer networks that can mimic visual skills such as recognizing objects, which the human brain does very accurately and quickly.
Time management skills keep animals primed for survival
Many animals may have a previously under-appreciated ability to make up for lost time with more effort, according to new research publishing this week in PLOS Computational Biology.
Ebola virus may replicate in an exotic way: Study indicates target for future drugs for measles, Ebola, RSV
University of Utah researchers ran biochemical analysis and computer simulations of a livestock virus to discover a likely and exotic mechanism to explain the replication of related viruses such as Ebola, ...
Life's underlying architecture shapes creation of proteins
Understanding how nature maps sequences of amino acids into the physical structure of the proteins they form is an old problem in biology, and a solution could open new doors to understanding the earliest ...
Solving the puzzle of cooperation in group environments
Research has shown that when two individuals meet repeatedly they are more likely to cooperate with one another. Flávio Pinheiro and colleagues from the Universities of Minho and Lisbon show that the most successful strategy ...
Geometry, programmed death might have enabled evolution of multicellularity
Geometry and programmed cell death may have helped along the evolution of multicellular life, according to new research led by SFI Omidyar Fellow Eric Libby.
Computer simulations visualize ion flux
Ion channels are involved in many physiological and pathophysiological processes throughout the human body. A young team of researchers led by pharmacologist Anna Stary-Weinzinger from the Department of Pharmacology ...
Should we listen to our genes, or does mother know best?
Breaking the mould of inherited family characteristics could help you survive in a fast-changing world, scientists have discovered.
Simulating in tiny steps gave birth to long-sought-after method
Using computer simulations to predict which drug candidates offer the greatest potential has thus far not been very reliable, because both small drug-like molecules and the amino acids of proteins vary so much in their chemistry. ...
Birds display lateralization bias when selecting flight paths
Flocks of birds manage to navigate through difficult environments by individuals having predispositions to favour the left- or right-hand side, according to research published in PLOS Computational Biology this week.
Can walkies tell who's the leader of the pack?
Dogs' paths during group walks could be used to determine leadership roles and through that their social ranks and personality traits, say researchers from Oxford University, Eötvös University, Budapest ...
Environment affects an organism's complexity
Scientists have demonstrated that organisms with greater complexity are more likely to evolve in complex environments, according to research published this week in PLOS Computational Biology. The researchers, based at Éc ...
Scientists explore the mechanisms of viruses' shells
The genome of viruses is usually enclosed inside a shell called capsid. Capsids have unique mechanic properties: they have to be resistant and at the same time capable of dissolving in order to release the ...
Study analyzes dynamical properties in antibiotic resistance enzyme
Antibiotic-resistant bacteria have been emerging at an alarming rate. In some of the scariest of these pathogens, the mechanism responsible for the bacteria's ability to defeat antibiotics is a complex protein ...
Researchers examine mechanical bases for the emergence of undulatory swimmers
How do fish swim? It is a simple question, but there is no simple answer.