PLoS Computational Biology is a peer-reviewed computational biology journal established in 2005 and published by the nonprofit Public Library of Science in association with the International Society for Computational Biology. Its Editor in Chief is Philip Bourne. All articles are open access and licensed under the Creative Commons Attribution License. The journal is well-known beyond its core field for its Ten Simple Rules series of articles that capture the essence of selected aspects of research in computational biology or in science more generally, e.g. how to present a poster, how to collaborate, or how to edit Wikipedia. Due to their free licensing, files from PLoS Computational Biology can be reused in places other than the journal s website, e.g. to illustrate Wikipedia articles.
Early infant growth rate linked to composition of gut microbiota
The composition of gut microbiota in a new-born baby's gut has been linked to the rate of early infant growth, reports research published this week in PLOS Computational Biology. The findings support the assertion that t ...
May 09, 2013
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Computer simulations reveal the energy landscape of ion channels
Every cell of our body is separated from its environment by a lipid bilayer. In order to maintain their biological function and to transduce signals, special proteins, so called ion channels, are embedded ...
May 03, 2013
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DNA: How to unravel the tangle
A research coordinated by the scientists at SISSA of Trieste has now developed and studied a numeric model of the chromosome that supports the experimental data and provides a hypothesis on the bundle's function.
Mar 29, 2013
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Robot ants successfully mimic real colony behavior
Scientists have successfully replicated the behaviour of a colony of ants on the move with the use of miniature robots, as reported in the journal PLOS Computational Biology.
Mar 28, 2013
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Under the hood of the ribosome
(Phys.org) —We all know—generally speaking—how a car works: The gas pedal makes it go, the break pedal makes it stop, and the steering wheel determines its course. But pop open the hood and you'll find ...
Mar 25, 2013
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Computer simulations yield clues to how cells interact with surroundings
(Phys.org) —Your cells are social butterflies. They constantly interact with their surroundings, taking in cues on when to divide and where to anchor themselves, among other critical tasks.
Mar 21, 2013
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Too small and numerous to count: Better ways to estimate the diversity of unseen life on and in our bodies
Target 'super-spreaders' to stop hepatitis C
Protein origami: Quick folders are the best
The evolutionary history of proteins shows that protein folding is an important factor. Especially the speed of protein folding plays a key role. This was the result of a computer analysis carried out by ...
Jan 31, 2013
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Was life inevitable? New paper pieces together metabolism's beginnings
(Phys.org)—Describing how living organisms emerged from Earth's abiotic chemistry has remained a conundrum for scientists, in part because any credible explanation for such a complex process must draw from fields spanning ...
Dec 13, 2012
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Researcher looks to whirligig beetle for bio-inspired robots
Whirligig beetles are named for their whirling movement on top of water, moving rapidly in and taking off into flight.
Nov 29, 2012
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Randomness forms complex social structures
(Phys.org)—The environment of group-living animals influences their social behaviour in a stronger way than was previously thought, says a new study from behavioural researchers at ETH and the University ...
Nov 29, 2012
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Music in our ears: The science of timbre
New research, published in PLOS Computational Biology, offers insight into the neural underpinnings of musical timbre. Mounya Elhilali, of Johns Hopkins University and colleagues have used mathematical models based on exp ...
Nov 01, 2012
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The hidden burden of bovine Tuberculosis
Up to 21% of herds clearing restrictions for bovine Tuberculosis (bTB) in Great Britain may be harbouring infection, according to a study published in PLOS Computational Biology this week. A cross-disciplinary group of exp ...
Oct 18, 2012
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Scientists build a clearer picture of the spread of bovine tuberculosis
Each year thousands of cattle are slaughtered to control the spread of bovine tuberculosis. New research reveals that testing misses many animals harbouring the disease and shows that large herds are particularly ...
Oct 18, 2012
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