Nucleic Acids Research is a peer-reviewed scientific journal published by Oxford University Press. It covers research on nucleic acids, such as DNA and RNA, and related work. Some of its content is available under an open access license. According to the Journal Citation Reports, the journal s 2010 impact factor is 7.836. The journal publishes two yearly special issues, one dedicated to biological databases, published in January since 1993 and the other on biological web servers, published in July since 2003.
Predictability: The brass ring for synthetic biology
(Phys.org) —Predictability is often used synonymously with "boring," as in that story or that outcome was soooo predictable. For practitioners of synthetic biology seeking to engineer valuable new microbes, ...
Protein abundant in cancerous cells causes DNA 'supercoiling'
A team of USC scientists has identified a protein that can change DNA topology, making DNA twist up into a so-called "supercoil."
How a microbial biorefinery regulates genes
Microorganisms that can break down plant biomass into the precursors of biodiesel or other commodity chemicals might one day be used to produce alternatives to petroleum. But the potential of this "biorefinery" ...
Discovery in synthetic biology takes us a step closer to new 'industrial revolution'
Scientists report that they have developed a method that cuts down the time it takes to make new 'parts' for microscopic biological factories from two days to only six hours.
Researchers study the structure of drug resistance in tuberculosis
(Phys.org) -- Edward Yu took note of the facts – nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally drug-resistant ...
Viruses with integrated gene switch
Scientists of the German Cancer Research Center have developed "RNA switches" which allow them to specifically turn on and off genes in viruses. This will help to enhance regulation of gene therapy and viral therapy of cancer.
Scientists use light to 'tag and track' genetic processes
(Phys.org) -- In a new study, UT Dallas researchers outline how they used fluorescent molecules to "tag" DNA and monitor a process called DNA looping, a natural biological mechanism involved in rearranging ...
NUS researchers identify a novel double-stranded DNA structure
By way of mechanical stretching, National University of Singapore researchers identify a novel double-stranded DNA structure, thus successfully resolving a 16-year-old scientific debate over the existence ...
Computer sleuthing helps unravel RNA's role in cellular function
Computer engineers may have just provided the medical community a new way of figuring out exactly how one of the three building blocks of life forms and functions.
Protein libraries in a snap
(PhysOrg.com) -- A Rice University undergraduate will depart with not only a degree but also a possible patent for his invention of an efficient way to create protein libraries, an important component of biomolecular ...