One of the most striking features of human genes is that genetic information required to produce proteins is stored in a discontinuous form, wherein the coding information (exons) is punctuated with non-coding segments known ...
Molecular & Computational biology
Apr 4, 2024
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10
Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using Vanderbilt's state-of-the-art instrumentation ...
Cell & Microbiology
Mar 18, 2024
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7
A new study from a team of McGill University and Vanderbilt University researchers is shedding light on our understanding of the molecular origins of some forms of autism and intellectual disability.
Molecular & Computational biology
Feb 26, 2024
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36
During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.
Molecular & Computational biology
Feb 26, 2024
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14
Are you sick and tired of getting sick and tired? A UNLV-led research team is exploring whether the reason we sometimes feel ill in the first place is because our body's cells suffer from trash that accumulates within them.
Cell & Microbiology
Feb 21, 2024
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62
Ubiquitin ligases regulate many processes in living cells. Depending on how many ubiquitin molecules they attach to the target proteins and in which way, they control the protein's fate.
Cell & Microbiology
Feb 8, 2024
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1
For decades it has been an open question in the ubiquitin research field how proteins are labeled as being defective or unneeded. In a recent study Brenda Schulman, Director at the Max Planck Institute (MPI) of Biochemistry, ...
Cell & Microbiology
Feb 7, 2024
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1
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. ...
Cell & Microbiology
Feb 5, 2024
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73
A recent re-emergence and outbreak of mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core. Now, a team of researchers from the Institute of Science and Technology Austria ...
Molecular & Computational biology
Feb 5, 2024
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7
In a complex called chromatin, long strands of DNA in cells' nuclei are tightly wrapped around a scaffolding of proteins, like a rolled-up ball of yarn. A new study by Weill Cornell Medicine investigators reveals that beyond ...
Cell & Microbiology
Jan 2, 2024
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