X-file cracked: Mini-key determines DNA shape

We finally know why our DNA has an X shape. This finding by researchers at the Netherlands Cancer Institute may have much broader implications for how our cells behave. "It looks like we have uncovered a universal mechanism ...

A molecular machine's secret weapon exposed

RNAs are having a moment. The foundation of COVID-19 vaccines, they've made their way from biochemistry textbooks into popular magazines and everyday discussions. Entire companies have been launched that are dedicated to ...

Formation of pores in mitochondrial membrane elucidated

Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40% of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important ...

CRISPR insight: How to fine-tune Cas protein's grip on DNA

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its target site on DNA. It's ...

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