Discovery of a mechanism for efficient autophagosome formation

Drs. Nobuo Noda (Director) and Tatsuro Maruyama (Researcher) et al. at the Institute of Microbial Chemistry (BIKAKEN, Tokyo, Japan) discovered that lipidated Atg8, the most famous factor that mediates autophagy, has membrane ...

An international study reveals how the 'guardian' of the genome works

Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre (CNIO) have discovered how certain proteins ensure the repair of errors introduced ...

Cloudy eyes caused by protein imbalance

Cataracts are the most common eye ailment in humans. However, the exact processes leading to this condition are not fully understood. A team of researchers headed by the Technical University of Munich (TUM) has now discovered ...

Chemists discover the structure of a key coronavirus protein

MIT chemists have determined the molecular structure of a protein found in the SARS-CoV-2 virus. This protein, called the envelope protein E, forms a cation-selective channel and plays a key role in the virus's ability to ...

Making cancer cells more susceptible to dying

Radiation and chemotherapy are designed to kill cancer cells. But for many patients, cancer cells can survive even after being hit with high doses of chemotherapy or radiation. To make treatment more effective, scientists ...

Revealing the identity of the last unknown protein of autophagy

Dr. Nobuo Noda and Dr. Kazuaki Matoba at the Institute of Microbial Chemistry discovered that Atg9, one of the proteins that function to mediate autophagy, has phospholipid-translocation activity (the lipid scramblase activity) ...

page 8 from 25