The hepatitis B virus (HBV) is responsible for one of the most serious and common infectious diseases. Transmitted through biological fluids, it attacks the liver cells. The chronic form of the disease can lead to serious ...
Cell & Microbiology
Oct 4, 2022
0
8
In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, they say, reveals ...
Cell & Microbiology
Sep 12, 2022
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142
A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19. The discovery could lead to the design of critically ...
Molecular & Computational biology
Sep 8, 2022
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65
Metabolic diseases, including diabetes, fatty liver, and obesity, have become a major "killer" affecting human health. Studies have shown that some orphan receptors could be targets for the treatment of these diseases. GPR119, ...
Biochemistry
Aug 18, 2022
0
21
The amount of salt and water in our cells and their pH is strictly controlled for cell survival. To maintain the necessary balance, special proteins perform the essential role of exchanging protons (hydrogen ions, or H+) ...
Cell & Microbiology
May 30, 2022
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71
To keep order in the tight quarters of the cell nucleus, our DNA is neatly clamped in place around a central disk by H1 linker histone, which helps shepherd DNA into the tidy chromatin fibers that comprise chromosomes. Linker ...
Molecular & Computational biology
May 27, 2022
0
40
A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.
Cell & Microbiology
May 19, 2022
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43
DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.
Molecular & Computational biology
Mar 21, 2022
0
73
When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.
Cell & Microbiology
Mar 21, 2022
0
35
A team led by Karolinska Institutet has combined Artificial Intelligence (AI) with structural biology to gain insights into two similar proteins that prevent bacterial infection in the urinary tract and the gastrointestinal ...
Biotechnology
Mar 11, 2022
0
129
