Nature Structural & Molecular Biology is an academic journal publishing research articles, reviews, news and commentaries in structural biology and molecular biology, with an emphasis on papers that further a "functional and mechanistic understanding of how molecular components in a biological process work together". One of the group of Nature journals, it is published by the Nature Publishing Group, a division of Macmillan Publishers Ltd. Founded in 1994 under the title Nature Structural Biology (ISSN: 1072-8368), the journal was renamed to the present title in January 2004. Like other Nature journals, there is no external Editorial Board, with editorial decisions being made by an in-house team, although peer review by external expert referees forms a part of the review process. Nature Structural & Molecular Biology is published monthly. Articles are archived online in text and PDF formats; access is by subscription only. Its 2009 impact factor was 12.273.
Same protein that fires up cancer-promoting Erk also blocks its activation
A protein which is intimately involved in cancer-promoting cell signaling also keeps a key component of the signaling pathway tied down and inactive, a team led by scientists from The University of Texas MD Anderson Cancer ...
Apr 19, 2013
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Scientists uncover the nuclear life of actin
A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.
Mar 24, 2013
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Selectively manipulating protein modifications
Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology ...
Mar 10, 2013
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Researchers solve the 3-D crystal structure of one of the most important human proteins
(Phys.org)—A research team at Weill Cornell Medical College has solved the 3D crystal structure of a member protein in one of the most important classes of human proteins—the G protein-coupled receptors ...
Feb 27, 2013
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Changes to DNA on-off switches affect cells' ability to repair breaks, respond to chemotherapy
Double-strand breaks in DNA happen every time a cell divides and replicates. Depending on the type of cell, that can be pretty often. Many proteins are involved in everyday DNA repair, but if they are mutated, ...
Feb 03, 2013
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What holds chromosomes together: Researchers elucidate the structure of dna-packaging proteins
To ensure that the genetic material is equally and accurately distributed to the two daughter cells during cell division, the DNA fibers must have an ordered structure and be closely packed. At the Max Planck ...
Jan 28, 2013
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Study details dimmer switch for regulating cell's read of DNA code
(Phys.org)—Epigenetics - the science of how gene activity can be altered without changes in the genetic code - plays a critical role in every aspect of life, from the differentiation of stem cells to the ...
Jan 08, 2013
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Dark matter made visible before the final cut
Research findings from the University of North Carolina School of Medicine are shining a light on an important regulatory role performed by the so-called dark matter, or "junk DNA," within each of our genes.
Jan 07, 2013
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New study defines the long-sought structure of a protein necessary for cell-cell interaction
Scientists know that cells in all higher organisms cells need to bind to each other for the development, architecture, maintenance and function of tissues. Mysteries have remained, however, about exactly ...
Jan 06, 2013
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Scientists discover how two proteins help keep cells healthy
Scientists at The Scripps Research Institute (TSRI) have determined how two proteins help create organelles, or specialized subunits within a cell, that play a vital role in maintaining cell health. This discovery opens the ...
Dec 02, 2012
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Study reports breakthrough in the understanding of embryonic stem cells
A significant breakthrough in the understanding of embryonic stem cells has been made by scientists from the Smurfit Institute of Genetics at Trinity College Dublin. The Trinity research group led by Dr Adrian Bracken and ...
Nov 30, 2012
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Scientists find missing link between players in the epigenetic code
Over the last two decades, scientists have come to understand that the genetic code held within DNA represents only part of the blueprint of life. The rest comes from specific patterns of chemical tags that ...
Sep 30, 2012
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Making and breaking heterochromatin
To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, ...
Sep 25, 2012
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Controlling gene expression: How chromatin remodelers block a histone pass
Two opposing teams battle it out to regulate gene expression on the DNA playing field. One, the activators, keeps DNA open to enzymes that transcribe DNA into RNA. Their repressor opponents antagonize that ...
Aug 26, 2012
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DESY X-ray source reveals decoy protein of a herpes virus at work
With the help of DESY's X-ray source DORIS III, an international team of scientists decoded an important weapon used by a widespread human herpes virus. The study reveals at the molecular level how the Epstein-Barr virus ...
Aug 23, 2012
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