Nature Methods

Decoding the cell's genetic filing system

A fully extended strand of human DNA measures about five feet in length. Yet it occupies a space just one-tenth of a cell by wrapping itself around histones—spool-like proteins—to form a dense hub of ...

dateApr 22, 2015 in Biochemistry
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First sensor for 'crowd control' in cells

University of Groningen scientists have developed a molecular sensor to measure 'crowding' in cells, which reflects the concentration of macromolecules present. The sensor provides quantitative information ...

dateFeb 02, 2015 in Biochemistry
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Single cells seen in unprecedented detail

Researchers have developed a large-scale sequencing technique called Genome and Transcriptome Sequencing (G&T-seq) that reveals, simultaneously, the unique genome sequence of a single cell and the activity ...

dateApr 27, 2015 in Biotechnology
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Predicting the fate of stem cells

University of Toronto researchers have developed a method that can rapidly screen human stem cells and better control what they will turn into. The technology could have potential use in regenerative medicine and drug development. ...

dateOct 22, 2013 in Cell & Microbiology
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A greasy way to take better protein snapshots

Thanks to research performed at RIKEN's SACLA X-ray free electron laser facility in Japan, the dream of analyzing the structure of large, hard-to-crystallize proteins and other bio molecules has come one step closer to reality. ...

dateNov 10, 2014 in Materials Science
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