Nature Methods

Single cells seen in unprecedented detail

Researchers have developed a large-scale sequencing technique called Genome and Transcriptome Sequencing (G&T-seq) that reveals, simultaneously, the unique genome sequence of a single cell and the activity ...

dateApr 27, 2015 in Biotechnology
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Decoding the cell's genetic filing system

A fully extended strand of human DNA measures about five feet in length. Yet it occupies a space just one-tenth of a cell by wrapping itself around histones—spool-like proteins—to form a dense hub of ...

dateApr 22, 2015 in Biochemistry
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Activating genes on demand

When it comes to gene expression - the process by which our DNA provides the recipe used to direct the synthesis of proteins and other molecules that we need for development and survival - scientists have ...

dateMar 04, 2015 in Biotechnology
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