Embryoids shed light on a complex genetic mechanism

Researchers from EPFL and the University of Geneva (UNIGE) have gained new insights into a mechanism regulating the early-stage development of mouse embryos. Instead of using an animal model, the team carried out their research ...

Uncovering new mechanisms for wheat rust resistance

Researchers have cloned the wheat rust resistance genes Lr9 and Sr43 and identified that they encode unusual kinase fusion proteins. The research, published in Nature Genetics, will enable new options for addressing resistance ...

Jumping genes in cancer cells open door to new immunotherapies

Jumping genes are short sections of DNA that have been incorporated randomly into the human genome over the long course of evolution. Also called transposable elements, these pieces of DNA have been implicated in the development ...

Researchers decipher comprehensive black-legged tick genome

A University of Maryland-led team of scientists has deciphered the first comprehensive, continuous genome for a parasite responsible for transmitting Lyme disease and other serious infections to hundreds of thousands of Americans ...

Machine learning method improves cell identity understanding

When genes are activated and expressed, they show patterns in cells that are similar in type and function across tissues and organs. Discovering these patterns improves our understanding of cells—which has implications ...

Key proteins keep DNA regions close for longer

New work by Friedrich Miescher Institute researchers shows that key proteins help to stabilize the interaction between otherwise highly dynamic DNA structures. The findings shed light onto how the complex folds that help ...

How chemical modifications on DNA keep genes silent

Several diseases, including certain types of cancer and some neurodevelopmental conditions, have aberrant patterns of DNA methylation, a chemical modification that regulates gene expression in ways that keep genes in the ...

Researchers solve pre-harvest sprouting in rice and wheat

Seed dormancy is an important survival tool for plants because it allows them to weather conditions not conducive to survival. At the same time, excessive dormancy may lessen cultivation time. In response, farmers often plant ...

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