Nature Chemical Biology is a monthly, peer-reviewed, scientific journal, which is published by Nature Publishing Group. It was first published in June 2005 (volume 1, issue 1). Terry L. Sheppard is a full-time professional editor with the title, "Chief Editor", and employed by Nature Chemical Biology. The impact factor for Nature Chemical Biology in 2010 is 15.808, according to the Journal Citation Reports. The publishing focus of Nature Chemical Biology is a forum for original research and commentary in Chemical-biology. Published topics encompass concepts and research methods in chemistry, biology, and related disciplines with the end result of controlling biological systems at the molecular level. Authors (contributors) are chemical biologists, also chemists involved in interdisciplinary research between chemistry and biology, along with biologists who produce research results in understanding and controlling biological processes at the molecular level. Interdisciplinary research in chemistry and biology is emphasized. The journal s main focus in this area is fundamental research which illuminates available chemical and biological tools, as well as mechanisms underpinning
New type of drug can target all disease-causing proteins
Current drugs block the actions of only about a quarter of known disease-causing proteins, but Yale University researchers have developed a technology capable of not just inhibiting, but destroying every protein it targets.
New findings shed light on fundamental process of DNA repair
Inside the trillions of cells that make up the human body, things are rarely silent. Molecules are constantly being made, moved, and modified—and during these processes, mistakes are sometimes made. Strands of DNA, for ...
New anti-microbial compounds evade resistance with less toxicity
New compounds that specifically attack fungal infections without attacking human cells could transform treatment for such infections and point the way to targeted medicines that evade antibiotic resistance.
Reaction snapshots of a notch-modifying enzyme provide a basis for drug design
Notch receptors are core components of the signaling pathways that regulate the development of cells within the human body. Notch signaling pathways can determine how cells proliferate or change during development, and defects ...
Calprotectin fends off microbial invaders by limiting access to iron
Invading microbial pathogens must scavenge essential nutrients from their host organism in order to survive and replicate. To defend themselves from infection, hosts attempt to block pathogens' access to these nutrients.
Researchers discover new enzyme, link to iron in vitamin A synthesis
A research team's discovery of new information about how plants synthesize carotenoids, precursors for vitamin A that are essential for plant development and survival, and human health, could help scientists increase the ...
Simple method for selective bioconjugation of native proteins
Mapping the folding process of a single membrane protein
Proteins are huge molecules containing hundreds to thousands of atoms that adopt a unique three dimensional structure, placing chemical groups in just the right place to catalyze reactions or build cellular structures. How ...
New 'TripAdvisor' site to address use of substandard biomedical research tools
An international panel of leading scientists is launching a new TripAdvisor-style website aimed at helping researchers choose better-quality research tools - and avoiding potentially serious errors in biomedical research.
Shining light on orphan receptors
Light has been used for the first time to activate a receptor for which the compound binding and controlling it naturally is unknown, as reported in Nature Chemical Biology today. A team of scientists including Harald Janovjak, ...