Nature Chemical Biology is a monthly, peer-reviewed, scientific journal, which is published by Nature Publishing Group. It was first published in June 2005 (volume 1, issue 1). Terry L. Sheppard is a full-time professional editor with the title, "Chief Editor", and employed by Nature Chemical Biology. The impact factor for Nature Chemical Biology in 2010 is 15.808, according to the Journal Citation Reports. The publishing focus of Nature Chemical Biology is a forum for original research and commentary in Chemical-biology. Published topics encompass concepts and research methods in chemistry, biology, and related disciplines with the end result of controlling biological systems at the molecular level. Authors (contributors) are chemical biologists, also chemists involved in interdisciplinary research between chemistry and biology, along with biologists who produce research results in understanding and controlling biological processes at the molecular level. Interdisciplinary research in chemistry and biology is emphasized. The journal s main focus in this area is fundamental research which illuminates available chemical and biological tools, as well as mechanisms underpinning
Chemical biologists find new halogenation enzyme
Molecules containing carbon-halogen bonds are produced naturally across all kingdoms of life and constitute a large family of natural products with a broad range of biological activities. The presence of halogen substituents ...
Microbial factories could produce locally brewed painkillers
The past few decades have seen enormous progress being made in synthetic biology – the idea that simple biological parts can be tweaked to do our bidding. One of the main targets has been hacking the biological ...
Bioengineers close to brewing opioid painkillers without using opium from poppies
For centuries poppy plants have been grown to provide opium, the compound from which morphine and other important medicines such as oxycodone are derived.
New tool identifies therapeutic proteins in a 'snap'
(Phys.org) —In human and bacterial cells, glycosylation – the chemical process of attaching complex sugar molecules to proteins – is as fundamental as it gets, affecting every biological mechanism from cell signaling ...
Researchers block plant hormone: Small molecule inhibits jasmonic acid, helps to explain its effects
Researchers trying to get new information about the metabolism of plants can switch off individual genes and study the resulting changes. However, Erich Kombrink from the Max Planck Institute for Plant Breeding ...
Protein evolution follows a modular principle
Proteins impart shape and stability to cells, drive metabolic processes and transmit signals. To perform these manifold tasks, they fold into complex three-dimensional shapes. Scientists at the Max Planck ...
Could boosting brain cells' appetites fight disease? New research shows promise
Deep inside the brains of people with dementia and Lou Gehrig's disease, globs of abnormal protein gum up the inner workings of brain cells – dooming them to an early death.
New approach for tuberculosis drugs
In the past 50 years, only one new tuberculosis drug has come on to the market, yet many more active substances are urgently needed. Current treatments increasingly fail due to multidrug-resistant pathogens. ...
Marine bacteria are natural source of chemical fire retardants
Researchers at the University of California, San Diego School of Medicine have discovered a widely distributed group of marine bacteria that produce compounds nearly identical to toxic man-made fire retardants.
New molecule enables quick drug monitoring
Monitoring the drug concentration in patients is critical for effective treatment, especially in cases of cancer, heart disease, epilepsy and immunosuppression after organ transplants. However, current methods are expensive, ...
Scientists provide new insights into biomass breakdown
Scientists at the University of York are playing a key role in the quest for a better understanding of how a recently discovered family of enzymes can degrade hard-to-digest biomass into its constituent sugars.
Scientists reveal structural secrets of enzyme used to make popular anti-cholesterol drug
In pharmaceutical production, identifying enzyme catalysts that help improve the speed and efficiency of the process can be a major boon. Figuring out exactly why a particular enzyme works so well is an altogether ...
Galectins direct immunity against bacteria that employ camouflage
Our bodies produce a family of proteins that recognize and kill bacteria whose carbohydrate coatings resemble those of our own cells too closely, scientists have discovered.
Green vaccination: boosting plant immunity without side effects
(Phys.org) —A team of international researchers has uncovered a mechanism by which plants are able to better defend themselves against disease causing pathogens.
Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works
Scientists have solved a decades-old medical mystery – and in the process have found a potentially less toxic way to fight invasive fungal infections, which kill about 1.5 million people a year. The researchers ...