A team of researchers working at the Francis Crick Institute has developed a way to find mutations in similar genome regions of cancer samples. In their paper published in the journal Nature Biotechnology, the group describes ...
Circular ribonucleic acids (circRNAs) are a promising platform for gene expression studies as a stable and prevalent ribonucleic acid in eukaryotic cells, which arise from back-splicing. In a new report now published in Nature ...
CRISPR-Cas9 has become one of the most convenient and effective biotechnology tools used to cut specific DNA sequences. Starting from Streptococcus pyogenes Cas9 (SpCas9), a multitude of variants have been engineered and ...
Biotechnology
Jun 26, 2020
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123
The CRISPR-Cas9 system has given researchers the power to precisely edit selected genes. Now, researchers have used it to develop a technology that can target any gene in the yeast Saccharomyces cerevisiae and turn it off ...
Biotechnology
May 7, 2018
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331
What exactly are the molecular interactions between the virus causing COVID-19 and its human host? How might our genetic differences cause different disease courses? And how do still-emerging virus variants differ in their ...
Biotechnology
Oct 10, 2022
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101
Scientists can now edit multiple sites in the genome at the same time to learn how different DNA stretches co-operate in health and disease.
Biotechnology
Mar 16, 2020
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1644
The largest study of CRISPR action to date has developed a method to predict the exact mutations CRISPR-Cas9 gene editing can introduce to a cell. Researchers at the Wellcome Sanger Institute edited 40,000 different pieces ...
Biotechnology
Nov 27, 2018
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213
It is currently challenging to directly observe the formation of intracellular nanostructures in the lab. In a new report, Miaomiao Zhang and a research team in chemistry, life sciences, medical engineering and science and ...
It's been nearly two decades since a UC Santa Cruz research team announced that they had assembled and posted the first human genome sequence on the internet. Despite the passage of time, enormous gaps remain in our genomic ...
Biotechnology
Mar 19, 2018
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40
Liver-on-a-chip cell culture devices are attractive biomimetic models in drug discovery, toxicology and tissue engineering research. To maintain specific liver cell functions on a chip in the lab, adequate cell types and ...
