Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains.
Cell & Microbiology
Nov 8, 2023
0
19
In a recent article published in Molecular Cell, Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, and Yuki Aoi Ph.D., a postdoctoral fellow in Shilatifard laboratory, ...
Cell & Microbiology
Nov 3, 2023
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66
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
Cell & Microbiology
Oct 31, 2023
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1
Researchers from Karolinska Institutet have discovered a new molecular mechanism by which cancer cells safeguard themselves from oncogene-induced replication stress and propose a strategy to deactivate this protective mechanism. ...
Cell & Microbiology
Aug 17, 2023
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45
Researchers from Heidelberg Medical Faculty, Heidelberg University Hospital and German Cancer Research Center investigate molecular relationships that promote infection and spread of SARS-CoV-2. The results may provide a ...
Cell & Microbiology
Jul 18, 2023
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66
A team of investigators in the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a novel protein region responsible for regulating ...
Cell & Microbiology
Jul 14, 2023
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25
Transcription factors could be the Swiss Army knives of gene regulation; they are versatile proteins containing multiple specialized regions. On one end they have a region that can bind to DNA. On the other end they have ...
Cell & Microbiology
Jul 5, 2023
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17
To keep their vital functions in balance, many organisms use small snippets of RNA to "silence" messenger RNAs that code for certain proteins. New research from FMI scientists has revealed a molecular hub that integrates ...
Molecular & Computational biology
Jun 27, 2023
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1
An international collaboration between two Danish and two German teams has delineated that the so-called "Arsenite resistance 2 (ARS2)" protein is capable of inducing early transcription termination by recruiting the termination ...
Cell & Microbiology
Jun 21, 2023
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7
During cell division, chromosomes, i.e., molecules containing our genetic material, must be properly replicated and segregated so that each daughter cell receives a complete and accurate set. Now, in an article published ...
Cell & Microbiology
Jun 8, 2023
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