Molecular biology ( /məˈlɛkjʊlər/) is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between the different types of DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated. Writing in Nature in 1961, William Astbury described molecular biology as Researchers in molecular biology use specific techniques native to molecular biology but increasingly combine these with techniques and ideas from genetics and biochemistry. There is not a defined line between these disciplines. The figure above is a schematic that depicts one possible view of the relationship between the fields: Much of the work in molecular biology is quantitative, and recently much work has been done at the interface of molecular biology and computer science in bioinformatics and computational biology. As of the early 2000s, the study of gene structure and function, molecular genetics, has been among the most

Publisher
American Society for Microbiology
Country
United States
History
1981–present
Website
http://mcb.asm.org/
Impact factor
5.942 (2008)

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What happens when good genes get lost?

Scientifically speaking, there is no bad DNA, though we like to blame it for unruly hair, klutziness or poor gardening skills. There is, however, junk DNA.

Lessons learned from yeast about human leukemia

The trifecta of biological proof is to take a discovery made in a simple model organism like baker's yeast and track down its analogs or homologs in "higher" creatures right up the complexity scale to people, in this case, ...

When cells sense the cue for growth

Researchers of the Genome Dynamics Project team at Tokyo Metropolitan Institute of Medical Science have revealed a new mechanism controlling cellular proliferation in response to serum, which triggers growth of resting cells.

Starvation causes atypical cell death

Researchers from the Cell death group of the Bellvitge Biomedical Research Institute (IDIBELL), led by Dr. Cristina Muñoz-Pinedo, have characterized the cell death process due to starvation, in which the endoplasmic reticulum ...