The Journal of Biological Chemistry (JBC) is a weekly peer-reviewed scientific journal that was established in 1905. Since 1925 it is published by the American Society for Biochemistry and Molecular Biology. It covers research in any area of biochemistry or molecular biology. The editor-in-chief is Herbert Tabor. All its articles are available free one year after publication. In press articles are available free on its website immediately after acceptance. The journal was established in 1905 by John Jacob Abel and Christian Archibald Herter, who also served as the first editors; the first issue appeared in October 1905. The location of the journal s editorial offices has included Cornell Medical College (until 1937), Yale University (1937–1958), Harvard University (1958–1967), and New York (from 1967). The journal is currently published by the American Society for Biochemistry and Molecular Biology (ASBMB) at the ASBMB offices in Rockville, Maryland. The following individuals have served as editors-in-chief: The editors of the Journal of Biological Chemistry have criticized the modern reliance upon the impact factor for ranking journals, noting that review articles, commentaries,
Researchers identify key enzyme found in bacteria responsible for heart valve disease
A disease-causing bacterium found in the mouth needs manganese, a trace mineral, in order to cause a serious heart infection, according to a preclinical study led by researchers at Virginia Commonwealth University ...
Huntington proteins and their nasty 'social network'
Researchers at the Buck Institute have identified and categorized thousands of protein interactions involving huntingtin, the protein responsible for Huntington's disease (HD). To use an analogy of a human social network, ...
Cell behaviour in low oxygen conditions mapped
(Phys.org) —Research at the University of Liverpool has explained how cells behave when placed in a low oxygen environment, a development that could have implications for cancer patients and other serious ...
New insight into protein misfolding in neurodegenerative disorders
Research by the University of Southampton has provided new insight into the consequence of accumulated 'misfolded proteins' in neurodegenerative disorders, such as Prion and Alzheimer's disease.
Solving a complex protein problem
Many proteins undergo processing within cellular compartments called the endoplasmic reticulum and the Golgi apparatus. Transit between these structures is facilitated by transport vesicles, which bubble ...
Proteomic analysis of tendon reveals disease stage-specific fragmentation of extracellular matrix proteins
In a series of articles, researchers in the Tendon Biology group at the RVC have established the importance of inflammatory mediators in acute tendon disease and the reduced ability to resolve inflammation in chronic disease ...
Recycling of 'chauffeur protein' helps regulate fat production
Studying a cycle of protein interactions needed to make fat, Johns Hopkins researchers say they have discovered a biological switch that regulates a protein that causes fatty liver disease in mice. Their findings, they report, ...
Researchers find novel approach for controlling deadly C. difficile infections
Researchers from the Alberta Glycomics Centre at the University of Calgary and the University of Alberta, in collaboration with researchers at the National Research Council of Canada in Ottawa, have revealed ...
Researchers find changes to protein SirT1
Researchers find changes to protein SirT1 can prevent excess metabolic stress associated with obesity, diabetes and aging.
Scientists develop promising drug candidates for pain, addiction
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have described a pair of drug candidates that advance the search for new treatments for pain, addiction and other disorders.
Scientists solve a sticky problem
(Medical Xpress)—Scientists have uncovered how an ulcer causing stomach bacteria, that has been linked to gastric cancer, sticks to and infects the lining of the stomach and gut.
Researchers find potential new treatment approach for pancreatic cancer
Scientists from The University of Manchester – part of Manchester Cancer Research Centre believe they have discovered a new way to make chemotherapy treatment more effective for pancreatic cancer patients.
HEXIM1 regulatory protein induces human pluripotent stem cells to adopt more specialized cell fate
A lot of optimism and promise surrounds the use of human pluripotent stem cells (hPSCs) for applications in regenerative medicine and drug discovery. However, technical challenges still hamper the culturing ...
Regulation of cancer-causing protein could lead to new therapeutic targets
Researchers with the Cincinnati Cancer Center (CCC) and the University of Cincinnati (UC) Cancer Institute have discovered a new regulation for the cancer-causing protein KRas which may help with the development of targeted ...
Researchers study evolution on the molecular level
The theory of evolution suggests that present-day organisms evolved from earlier life forms.