Genome Biology

Genomics is a discipline in genetics concerned with the study of the genomes of organisms. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome s networks. For the United States Environmental Protection Agency, "the term "genomics" encompasses a broader scope of scientific inquiry associated technologies than when genomics was initially considered. A genome is the sum total of all an individual organism s genes. Thus, genomics is the study of all the genes of a cell, or tissue, at the DNA (genotype), mRNA (transcriptome), or protein (proteome) levels." The

Publisher
BioMed Central
Country
United Kingdom
History
2000–present
Impact factor
6.89 (2011)
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Very berry study aims to improve wine quality

A gene expression study of grapevine berries grown in different Italian vineyards has highlighted genes that help buffer the plants against environmental change and may explain the different quality performances of grapevine ...

Jun 06, 2013 not rated yet 0

Biologists decode turtle genome

A group of 50 researchers from around the globe, including biology professors Daniel Warren, Ph.D., from Saint Louis University and Leslie Buck, Ph.D., from the University of Toronto, have spent the last ...

Apr 23, 2013 not rated yet 0

Pining for a beetle genome

The sequencing and assembly of the genome of the mountain pine beetle, Dendroctonus ponderosae, is published online this week in Genome Biology. The species is native to North America, where it is current ...

Mar 26, 2013 not rated yet 0

Wasp transcriptome creates a buzz

New research delivers a sting in the tail for queen wasps. Scientists have sequenced the active parts of the genome – or transcriptome – of primitively eusocial wasps to identify the part of the genome that makes you ...

Feb 25, 2013 4.5 / 5 (2) 0

Honey bees fight back against Varroa

The parasitic mite Varroa destructor is a major contributor to the recent mysterious death of honey bee (Apis mellifera) colonies. New research published in BioMed Central's open access journal Genome Biolog ...

Sep 27, 2012 4.8 / 5 (11) 2 | with audio podcast

3Qs: New clues to unlocking the genome

Last week, Nature Mag­a­zine, Genome Research and Genome Biology pub­lished 30 papers on break­through research that will change the face of genetics. After nearly a decade of searching, the Ency­clo­pedia ...

Sep 19, 2012 5 / 5 (1) 0