ChemMedChem is a monthly peer-reviewed medicinal chemistry journal. It is co-owned by the 14 European chemical society members of ChemPubSoc Europe and is published by Wiley-VCH. Its 2010 impact factor is 3.306. In addition to original research in the form of full papers and shorter communications, ChemMedChem contains review-type articles (reviews, minireviews, essays, highlights) as well as occasional book reviews and conference reports. The first volume was published at the beginning of 2006 under the two founding chemical societies, the German Chemical Society (GDCh) and the Italian Chemical Society (SCI). Since then, 12 additional chemical societies have joined in co-ownership of the journal. ChemMedChem is a sister publication to other scientific journals published by Wiley-VCH, including Angewandte Chemie, ChemBioChem, ChemPhysChem, ChemSusChem, and ChemCatChem. Topics covered in ChemMedChem include drug design, development and delivery, molecular modeling, combinatorial chemistry, drug target validation, lead generation, and ADMET studies.
An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists.
Biochemistry
Mar 24, 2015
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A team of interdisciplinary researchers from the Institut National de la Recherche Scientifique (INRS) is hoping to identify effective COVID-19 therapeutics. With help from the Canadian Light Source (CLS) at the University ...
Biochemistry
Sep 28, 2022
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9
While the first vaccines have been developed against the pathogen SARS-CoV-2, studies are still underway to identify effective drugs for treating coronavirus infections. Scientists in Gießen, Mainz, and Würzburg in Germany ...
Molecular & Computational biology
Jan 18, 2021
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10
The research group of Prof. Antonio M. Echavarren at ICIQ has designed and synthetized a series of analogues of (-)-Englerin A that are highly selective and effective in the growth-inhibition of renal cancer cells.
Biochemistry
May 2, 2016
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4
A group of biologists, theoretical chemists and synthetic chemists at ITbM have come together to develop a small molecule that slows down the circadian clock rhythm through binding to the CRY clock protein.
Biochemistry
Feb 8, 2016
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11
A tsetse fly bites a girl. She becomes itchy, feverish, and her joints ache. Weeks later, she loses coordination and some sensation in her limbs. It becomes difficult to think, to sleep.
Biochemistry
Oct 6, 2014
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0
Molecules that bind and illuminate proteins specific to tumor cells are key to detecting cancer as early as possible. The cyclooxygenase-2 (COX-2) enzyme is just such a protein, as the concentration of COX-2 is greater in ...
Biochemistry
Nov 7, 2013
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0
(Phys.org)—Iodide entrapment in the thyroid gland is essential, and plays a key role in dysfunctions such as thyroid and breast cancers, thyroiditis, Graves–Basedow disease, and Hashimoto's disease. The accidents at Chernobyl ...
Biochemistry
Nov 8, 2012
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0
(Phys.org) -- Many drug candidates fail because of low solubility or poor pharmacokinetic behavior. Ron Raines and colleagues at the University of Wisconsin–Madison (USA) have devised a new prodrug strategy to overcome ...
Biochemistry
Aug 6, 2012
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0
(Phys.org) -- New drug candidates require testing in animal models prior to approval for clinical use. A recently developed antagonist based on a bicyclic peptide inhibited the human serine protease plasma kallikrein potently ...
Biochemistry
Apr 13, 2012
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