Chemistry & Biology publishes reports of novel investigations in all areas at the interface of chemistry and biology. Chemistry & Biology strongly encourages submission of articles in which chemical tools are used to provide unique insight into biological function and mechanism. Studies that illustrate the underlying chemistry of biological processes will also be viewed favorably. Other relevant studies of interest to chemists and biologists will also be considered. In general, to be considered suitable for publication in this journal, investigations that primarily have a genetic, computational, or theoretical focus must contain substantiating experimental data. All articles should not only be of significance to the immediate field but should also be of interest to our diverse readership from the broad chemical-biology community.
Drug side effects examined
Yellow vision, pseudo-pulmonary obstruction, involuntary body movements, respiratory paralysis. These are some of the 1,600 known side effects (SEs) produced by drugs. Adverse effects are one of the main ...
Apr 19, 2013
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Study identifies chemical compounds that halt virus replication
Researchers at Boston University School of Medicine (BUSM) have identified a new chemical class of compounds that have the potential to block genetically diverse viruses from replicating. The findings, published ...
Mar 21, 2013
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Team develops psoriasis drug
Ben-Gurion University of the Negev (BGU) researchers, in collaboration with Teva Pharmaceutical Industries Ltd., have developed a promising drug candidate to treat psoriasis. The finding was reported in a new paper published ...
Mar 20, 2013
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Pathway for membrane building blocks
Biomembranes consist of a mosaic of individual, densely packed lipid molecules. These molecules are formed inside the cells. But how do these building blocks move to the correct part of the membrane? Researchers ...
Jan 30, 2013
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Tomorrow's life-saving medications may currently be living at the bottom of the sea
OHSU researchers, in partnership with scientists from several other institutions, have published two new research papers that signal how the next class of powerful medications may currently reside at the bottom of the ocean. ...
Jan 29, 2013
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How signal molecules for the formation of various cell types are controlled
The regulation of important signal molecules that are critical for the formation of various cell types can be influenced by a chemically produced variant of indirubin, a natural material used in traditional Chinese medicine. ...
Nov 30, 2012
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Battles between steroid receptors to regulate fat accumulation
The androgen receptor in human cells inhibits fat accumulation, but its activity can be sabotaged by glucocorticoids, steroids that regulate fat deposition and are known drivers of obesity and insulin resistance, said researchers ...
Sep 20, 2012
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'Naked Darth Vader' approach could tame antibiotic resistant superbugs
Rather than trying to kill bacteria outright with drugs, Université de Montréal researchers have discovered a way to disarm bacteria that may allow the body's own defense mechanisms to destroy them.
Aug 23, 2012
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Scientists find a way to make disease-causing proteins vulnerable to drugs
(Phys.org) -- One of the most daunting challenges facing pharmaceutical scientists today are “undruggable proteins” – the approximately 80% of proteins involved in human disease that do not ...
Jul 27, 2012
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Studying fish to learn about fat
In mammals, most lipids (such as fatty acids and cholesterol) are absorbed into the body via the small intestine. The complexity of the cells and fluids that inhabit this organ make it very difficult to study in a laboratory ...
Jun 28, 2012
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New candidate drug stops cancer cells, regenerates nerve cells
Scientists have developed a small-molecule-inhibiting drug that in early laboratory cell tests stopped breast cancer cells from spreading and also promoted the growth of early nerve cells called neurites.
Jun 21, 2012
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New anti-inflammatory drugs pinch off reactive oxygen species at the source
Scientists at Emory University School of Medicine have identified a new type of anti-inflammatory compound that may be useful in treating a wide range of conditions, including neurodegenerative and autoimmune diseases. These ...
Jun 21, 2012
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