Cell is a peer-reviewed scientific journal publishing research papers across a broad range of disciplines within the life sciences. Areas covered include molecular biology, cell biology, systems biology, stem cells, developmental biology, genetics and genomics, proteomics, cancer research, immunology, neuroscience, structural biology, microbiology, virology, physiology, biophysics, and computational biology. The journal was established in 1974 by Benjamin Lewin and is published twice monthly by Cell Press, an imprint of Elsevier. Benjamin Lewin founded Cell in January 1974, under the aegis of MIT Press. He then bought the title and established an independent Cell Press in 1986. In April 1999, Lewin sold Cell Press to Elsevier. The "Article of the Future" feature was the recipient of a 2011 PROSE Award for Excellence in Biological & Life Sciences presented by the Professional and Scholarly Publishing Division of the Association of American Publishers. According to ScienceWatch, the journal was ranked first overall in the category of highest-impact journals (all fields) over 1995–2005 with an average of 161.2 citations per paper. According to the Journal Citation Reports, the journal
Study points to unexplored realm of protein biology, drug targets
Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins.
How RNA machinery navigates our genomic obstacle course
Once upon a time, scientists thought RNA polymerase—the molecule that kicks off protein synthesis by transcribing DNA into RNA—worked like a wind-up toy: Set it down at a start site in our DNA and it would whir steadily ...
Single enzyme's far-reaching influence in human biology and disease
Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.
X-ray study may aid in designing better blood pressure drugs
An experiment at the Department of Energy's SLAC National Accelerator Laboratory has revealed in atomic detail how a hypertension drug binds to a cellular receptor that plays a key role in regulating blood pressure. The results ...
Advances in technology and computational analysis paving the way for translational studies
The Human Genome Project gave us an incredible foundation from which to understand our potential genetic repertoire. In order to understand the actual roles of particular genes in disease, however, it is not only critical ...
Gut instinct: How intestinal stem cells find their niche
Mommy, where do intestinal stem cells come from? All right, it's not likely a kindergartner would ask such a question. But evolutionary biologists want to know.
Microbes help produce serotonin in gut
Although serotonin is well known as a brain neurotransmitter, it is estimated that 90 percent of the body's serotonin is made in the digestive tract. In fact, altered levels of this peripheral serotonin have been linked to ...
Video: Napoleon Bonaparte and the insulin revolution
A team of Sydney researchers has drawn inspiration from a 19th century map, commissioned by Napoleon to chart his defeat in Russia, to show how insulin works in the human body.
First steps in basic biological process that could be harnessed to make therapeutic cells
Understanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves. By knowing the principles that underlie ...
Plant receptors with built-in decoys make pathogens betray themselves
Receptors carrying built-in decoys are the latest discovery in the evolutionary battle between plants and pathogens. The decoy domains within the receptor detect pathogens and raise the cell's alarm when there is an infection.