Mapping enzyme catalysis with metabolic sensing

Enzymes maintain a range of protein sequences and diverse structural forms with activities that far exceed the best chemical catalysts. However, research on engineering them with new and improved features are limited due ...

Lighting up chemical reactions for sustainable drug production

Researchers have discovered a new approach for using visible-light to structurally modify bioactive molecules in chemical reactions, providing a possible sustainable alternative to traditional methods that could be used in ...

Understanding enzyme evolution paves the way for green chemistry

Researchers at the University of Bristol have shown how laboratory evolution can give rise to highly efficient enzymes for new-to-nature reactions, opening the door for novel and more environmentally friendly ways to make ...

Machine learning discovers new sequences to boost drug delivery

Duchenne muscular dystrophy (DMD), a rare genetic disease usually diagnosed in young boys, gradually weakens muscles across the body until the heart or lungs fail. Symptoms often show up by age 5; as the disease progresses, ...

Biological engineers find a new target for malaria drugs

Every year, more than 200 million people are infected with malaria, and nearly 500,000 die from the disease. Existing drugs can treat the infection, but the parasite that causes the disease has evolved resistance to many ...

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