How a Silly Putty ingredient could advance stem cell therapies
The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become, a University of Michigan study shows.
Synthetic gene circuits pump up cell signals
(Phys.org) —Synthetic genetic circuitry created by researchers at Rice University is helping them see, for the first time, how to regulate cell mechanisms that degrade the misfolded proteins implicated ...
Radiation able to be securely stored in nontoxic molecule, study finds
Researchers have discovered that microscopic "bubbles" developed at Kansas State University are safe and effective storage lockers for harmful isotopes that emit ionizing radiation for treating tumors.
Chemists devise a new way to manufacture peptide drugs, which hold promise for treating many diseases
Small protein fragments, also called peptides, are promising as drugs because they can be designed for very specific functions inside living cells. Insulin and the HIV drug Fuzeon are some of the earliest ...
Study shows short peptides can self-assemble into catalysts
Structure of sodium channels different than previously believed
Sodium channels are implicated in many serious conditions such as heart disease, epilepsy and pain, making them an important potential target for drug therapies. Unfortunately, there is still much scientists do not know about ...
Breakthrough points to new drugs from nature
Researchers at Griffith University's Eskitis Institute have developed a new technique for discovering natural compounds which could form the basis of novel therapeutic drugs.
Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works
Scientists have solved a decades-old medical mystery – and in the process have found a potentially less toxic way to fight invasive fungal infections, which kill about 1.5 million people a year. The researchers ...
Penicillin redux: Rearming proven warriors for the 21st century
Penicillin, one of the scientific marvels of the 20th century, is currently losing a lot of battles it once won against bacterial infections. But scientists at the University of South Carolina have just reported ...
Researchers show fruit flies have latent bioluminescence
New research from Stephen C. Miller, PhD, associate professor of biochemistry and molecular pharmacology, shows that fruit flies are secretly harboring the biochemistry needed to glow in the dark—otherwise ...
Researchers develop new tool to check cells' 'batteries'
(Medical Xpress)—Under the microscope, they glow like streetlights, forming tidy rows that follow the striations of muscle tissue. They are mitochondria – the powerhouses of cells – and researchers ...
Antibiotic resistance enzyme caught in the act
Resistance to an entire class of antibiotics – aminoglycosides—has the potential to spread to many types of bacteria, according to new biochemistry research.
Chemists' work with small peptide chains may revolutionize study of enzymes and diseases
Chemists in Syracuse University's College of Arts and Sciences have, for the first time, created enzyme-like activity using peptides that are only seven amino acids long.
Chemical probe profiles live-cell organelle activity, adds to understanding of lysosome dynamics
A team of scientists from Pacific Northwest National Laboratory synthesized a chemical activity-based probe (ABP) that can provide new information about how living cells function. The new ABP is designed ...